2-phenyl pyrimidines which are tubulin inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S326000, C546S268100

Reexamination Certificate

active

07981900

ABSTRACT:
Compounds of general formula (I), (II) (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).

REFERENCES:
patent: 4367790 (1983-01-01), Draeger
patent: 4676301 (1987-06-01), Sakamoto
patent: 82 928 (1895-10-01), None
patent: 0 967 452 (1999-12-01), None
patent: 352 807 (1905-08-01), None
patent: 253816 (1926-06-01), None
patent: 1027717 (1966-04-01), None
patent: 2000180093 (2000-06-01), None
patent: WO 02/47690 (2002-06-01), None
patent: WO-02/060492 (2002-08-01), None
patent: WO-03/026661 (2003-04-01), None
patent: WO-03/031406 (2003-04-01), None
patent: WO-03/099796 (2003-12-01), None
patent: WO-2004/052868 (2004-06-01), None
Jordan, V. C. Nature Reviews: Drug Discovery, 2, 2003, 205.
Vippagunta, et al. Advanced Drug Delivery Reviews, 48, 2001, 18.
Chawla, et al. Curr. Res. & Info. Pharm. Sci. (CRIPS), 5, 1, 2004, 9-12.
Wolff, Manfred E., Ed. Burger's Medicinal Chemistry and Drug Discovery—Fifth Edition, New York: John Wiley & Sons, 1996, vol. 1, 975-976.
International Search Report for PCT/AU2004/001689, mailed on Feb. 3, 2005, 3 pages.
Jordan and Wilson, Curr. Opin. Cell Biol. (1998) 10:123-130.
Jordan et al., J. Mol. Biol. (1986) 187:61-73.
Rai and Wolff, J. Biol. Chem. (1996) 271:14707-14711.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

2-phenyl pyrimidines which are tubulin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-phenyl pyrimidines which are tubulin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-phenyl pyrimidines which are tubulin inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2685086

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.