Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-01-27
1994-08-09
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540302, C07D48700, A61K 31395, A01N 4300
Patent
active
053366743
ABSTRACT:
The present invention relates to antibacterial agents of the carbapenem class, in which the 2-position sidechain is characterized by a phenanthridine moiety typically having a substituent attached to the nitrogen of the phenanthridine and substituted at other positions by various neutral substituents. When there is substitution on the nitrogen of the phenathridine moiety that nitrogen is a charged quaternary nitrogen.
REFERENCES:
patent: 4260627 (1981-04-01), Christensen et al.
patent: 4465632 (1984-08-01), Christensen et al.
patent: 4543257 (1985-09-01), Cama et al.
patent: 4978659 (1989-08-01), Salzmann et al.
patent: 5004739 (1991-04-01), Salzmann et al.
patent: 5004740 (1991-04-01), Salzmann et al.
patent: 5006519 (1991-04-01), DiNinno et al.
patent: 5011832 (1991-04-01), Salzmann et al.
patent: 5035385 (1991-07-01), DiNinno et al.
patent: 5037820 (1991-08-01), DiNinno et al.
patent: 5132422 (1992-07-01), DiNinno et al.
patent: 5153185 (1992-10-01), DiNinno et al.
patent: 5157033 (1992-10-01), DiNinno et al.
patent: 5162314 (1992-11-01), DiNinno et al.
L. D. Cama et al., Total Synthesis of Theinamycn Analgos-III, Tetrahedron 39, 2531 (1983).
R. N. Guthikonda et al., Structure Activity Relationships in the 2-Arylcarbapenem Series, J. Med. Chem., 30, 871 (1987).
DiNinno Frank P.
Greenlee Mark L.
Lee Wendy
Rano Thomas A.
Cintins Marianne M.
Cook Rebecca
Daniel Mark D.
DiPrima Joseph F.
Merck & Co. , Inc.
LandOfFree
2-phenanthridinyl carbaphenem antibacterial agent does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-phenanthridinyl carbaphenem antibacterial agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-phenanthridinyl carbaphenem antibacterial agent will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-216168