2-Oxopropionaldehyde bis(thiosemicarbazone) protein derivatives,

Details 2-Oxopropionaldehyde bis(thiosemicarbazone) protein derivatives, 2-Oxopropionaldehyde bis(thiosemicarbazone) protein derivatives,

1980-08-14

1982-07-06

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2601125R, 260113, 260121, 260112B, 424 1, C07G 700, C07G 704

Patent

active

043382487

ABSTRACT:
A radioactive diagnostic agent which comprises a protein and a radioactive metallic element combined with intervention of a bifunctional chelating agent of the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each a hydrogen atom or a C.sub.1 -C.sub.3 alkyl group and is characteristic in having high stability even after administered into a human body.

REFERENCES:
patent: 3824276 (1974-07-01), Murray et al.
patent: 3862299 (1975-01-01), Bruno et al.
patent: 3863004 (1975-01-01), Wolfangel
patent: 4010251 (1977-03-01), Green
Nishimura et al., Yakugaku Zasshi, 97, pp. 671-675, (1977).
Chem. Abstracts vol. 87, 1977, 193633m, Nishimura et al.

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