2-oxoethyl derivatives as immunosuppressants

Details 2-oxoethyl derivatives as immunosuppressants 2-oxoethyl derivatives as immunosuppressants

1995-04-28

1997-11-11

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

548537, 546245, C07K 5078, A61K 3805

Patent

active

056864248

ABSTRACT:
A class of compounds that suppress human T-lymphocyte proliferation is disclosed. The active compounds essentially contain at least the following structure: ##STR1##

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patent: 4894366 (1990-01-01), Okuhara et al.
patent: 4981792 (1991-01-01), Inamine et al.
patent: 5011943 (1991-04-01), Wang
patent: 5057608 (1991-10-01), Wyvratt et al.
Ciabatti, Farmaco 43 (12)989 (1988).
Hauske et al., Design and Synthesis of Novel FKPB Inhibitors J. Med. Chem., 35:4284-4296 (1992).

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