2-oxo-pyrido[2,3-g]quinoline derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D47104

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active

049392590

ABSTRACT:
Trans-(.+-.)-2-(substituted)-6-(substituted)-5,5a,6,7,8,9,9a,10-octahydroph rido[2,3-g]quinolines are useful in treating a variety of disorders including Parkinsonism, anxiety, depression, hypertension, glaucoma, sexual dysfunction, and prolactin mediated disorders such as galactorrhea, amenorrhea, prolactinoma and the inhibition of postpartum lactation.

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patent: 4659832 (1987-04-01), Schaus et al.
Bach et al., J. Med. Chem., 23, 481, (1980).
Nordman et al., J. Med. Chem., 28(3), 367 (1985).

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