(2-oxo-3-methylene-1,2,3,5-tetrahydroimidazo[2,1-b]q uinazolinyl

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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260544N, 514267, 544115, 544250, 544165, 544387, 546146, 546164, 546166, 546226, 548491, 548540, 560 23, 562434, 564142, 564166, A61K 31505, C07D48704

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046704345

ABSTRACT:
This invention relates to compounds of the formula ##STR1## and the pharmaceutically acceptable acid addition salts thereof wherein the various substituents are defined herein. These compounds are cyclic AMP phosphodiesterase inhibitors useful as antithrombotic and inotropic agents in mammals.

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patent: 4070470 (1978-01-01), Nakagawa et al.
patent: 4313947 (1982-02-01), Nakagawa et al.
patent: 4490371 (1984-12-01), Jones et al.
patent: 4596806 (1986-06-01), Ishikawa et al.
European Journal of Medicinal Chemistry, 1982-17, No. 6d, pp. 547-556 by Keinzle et al.
Journal of Pharmacology and Experimental Therapeutics, vol. 211, No. (1979), pp. 26-30 by Hidaka et al.

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