2-Oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines

Details 2-Oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines 2-Oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines

1987-12-23

1989-10-03

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540357, 540360, 540364, C07D40312, C07D40114, C07D41714, A61K 31505

Patent

active

048718416

ABSTRACT:
Antibacterial activity is exhibited by 2-azetidinones having a 3-acylamino substituent and having an activating group in the 1-position of the formula ##STR1## wherein R.sub.4 is ##STR2## wherein A.sub.1 is a single bond, ##STR3## --NH-- or ##STR4## A.sub.2 is a single bond, --NH--, --CH.sub.2 --CH.sub.2 --NH-- or ##STR5## A.sub.3 is a single bond, --CH.dbd.CH--, --(CH.sub.2).sub.t --, --NH--(CH.sub.2).sub.p -- or ##STR6## wherein t is 1, 2, 3 or 4 and p is 0 or 1; and A.sub.4 is a single bond --CH.sub.2 --, --NH--CH.sub.2 --, or --N.dbd.CH--.

REFERENCES:
patent: 4587047 (1986-05-01), Breuer et al.
patent: 4743685 (1988-05-01), Breuer

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