Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1982-09-07
1984-05-15
Rizzo, Nicholas S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424270, 424271, 2602391, C07D49900, A61K 31425
Patent
active
044487320
ABSTRACT:
Certain novel 2-oxo-1,3-dioxol-4-ylmethyl esters of penicillanic acid 1,1-dioxide (sulbactam) hydrolyze readily in vivo to liberate the corresponding free acid. The novel esters of this invention are useful therefore as antibacterial agents and beta-lactamase inhibitors.
REFERENCES:
patent: 4234579 (1980-11-01), Barth
patent: 4359472 (1982-11-01), Hamanaka
patent: 4389408 (1983-06-01), Sakamoto et al.
Frost Albert E.
Knuth Charles J.
Lumb J. Trevor
Pfizer Inc.
Rizzo Nicholas S.
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