2-Oxo-1,3-dioxol-4-ylmethyl esters of penicillanic acid 1,1-diox

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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Details

424270, 424271, 2602391, C07D49900, A61K 31425

Patent

active

044487320

ABSTRACT:
Certain novel 2-oxo-1,3-dioxol-4-ylmethyl esters of penicillanic acid 1,1-dioxide (sulbactam) hydrolyze readily in vivo to liberate the corresponding free acid. The novel esters of this invention are useful therefore as antibacterial agents and beta-lactamase inhibitors.

REFERENCES:
patent: 4234579 (1980-11-01), Barth
patent: 4359472 (1982-11-01), Hamanaka
patent: 4389408 (1983-06-01), Sakamoto et al.

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