2-oxindole compounds which have useful tyrosine kinase activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546141, 546142, 546145, 546146, 546147, 546148, 546152, 546153, 546155, 546157, 546158, 546174, 546176, 546177, 546178, 546179, 546180, 548458, 514314, 514307, 514309, 514415, 514418, 514419, C07D40106, A61K 3147, A61K 31405

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054880572

ABSTRACT:
The present invention provides novel aryl- and heteroarylethenylene derivatives which are useful as tyrosine kinase activity inhibitors.

REFERENCES:
patent: 5122537 (1992-06-01), Buzzetti et al.
patent: 5130472 (1992-07-01), Buzzetti et al.
Hodges et al, Canadian Journal of Chemistry, vol. 46, No. 13, Jul. 1, 1968, pp. 2189-2194.
von Sobneck et al, Chem. Ber, vol. 102 (4), (1969) pp. 1347-1356.
Il Farmaco 48 (5), 615-636 (1993) by Buzzetti F. et al.

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