2-(.omega.-Alkylaminoalkyl)- and 2-(.omega.-dialkylaminoalkyl-3-

Details 2-(.omega.-Alkylaminoalkyl)- and 2-(.omega.-dialkylaminoalkyl-3- 2-(.omega.-Alkylaminoalkyl)- and 2-(.omega.-dialkylaminoalkyl-3-

1983-08-01

1985-11-05

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514416, 544144, 548465, 548472, A61K 3140, C07D20946, C07D41106

Patent

active

045514534

ABSTRACT:
The 2-(.omega.-alkylaminoalkyl)- and 2-(.omega.-dialkylaminoalkyl)-3-(4-X-benzylidene)phthalimidines are useful as local anesthetics. For the preparation, the adduct is formed between the suitable 3-(4-X-benzylidene)phthalide and a substituted amino-alkylamine, the adduct being then reacted with acetic anhydride; the X substituent at the position 4 of the benzylidene group then can be suitably converted according to the requirements.

REFERENCES:
patent: 2957872 (1960-10-01), Huebner
patent: 3031458 (1962-04-01), Huebner
patent: 3091568 (1963-05-01), Bub

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