2-O-pyrimidinyl glycerol derivatives

Details 2-O-pyrimidinyl glycerol derivatives 2-O-pyrimidinyl glycerol derivatives

1988-08-03

1990-04-24

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

514252, 514269, 514274, 544120, 544122, 544123, 544216, 544238, 544239, 544240, 544241, 544295, 544319, 544357, 544408, C07D23934

Patent

active

049201344

ABSTRACT:
Novel compounds having the formula: ##STR1## wherein ##STR2## represents a nitrogen-containing aromatic 6-membered ring; R.sup.1 represents a higher alkyl group which may be substituted; R.sup.2 represents a tertiary amino group or a quaternary ammonium group; and m represents 2 or 3; and salts thereof have superior antitumor activities including differentiation-inducing activity, and are useful as antitumor agents.

REFERENCES:
patent: 4027027 (1977-05-01), Jeggi
patent: 4294966 (1981-10-01), Zergenyi
patent: 4438128 (1984-03-01), Wiedemann
patent: 4460588 (1984-07-01), Serban
patent: 4618609 (1986-10-01), Acker
patent: 4731373 (1988-03-01), Barner
Chem. Abstr., vol. 109, Entry 93527j, abstracting EP 254,540, pub. 27 Jan. 1988.

Affiliated with

Also associated with

Rating

2-O-pyrimidinyl glycerol derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-O-pyrimidinyl glycerol derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-O-pyrimidinyl glycerol derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-34987