2'-O-aminooxy-modified oligonucleotides

Details 2'-O-aminooxy-modified oligonucleotides 2'-O-aminooxy-modified oligonucleotides

1998-01-30

2000-10-03

Crane, L. Eric

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 276, 536 278, 536 2781, 536 285, 536 267, 536 268, 536 2853, 558 70, C07H 2102, C07H 1906, C07H 1916

Patent

active

061275336

ABSTRACT:
Nucleotide compositions containing aminooxy moieties are provided. In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligonucleotide is modified to include an aminooxy moiety.

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