2'-O-alkylthioalkyl and 2'-C-alkylthioalkyl-containing nucleic a

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 6, 435 9131, 435179, 435366, 536 231, 536 243, 536 251, 514 44, C07H 2104, C07H 2100, C12Q 168, A61K 4800

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active

058408762

ABSTRACT:
A compound having the formula: ##STR1## wherein, R1 represents 2'-O-R.sub.3 -thio-R.sub.3 and/or 2'-C-R.sub.3 -thio-R.sub.3, wherein R.sub.3 is independently a compound selected from a group consisting of alkyl, alkenyl, alkynyl, aryl, alkylaryl, carbocyclic aryl, heterocyclic aryl, amide and ester; X represents a base or H; Y represents a phosphorus-containing group; and R2 represents H, DMT or a phosphorus-containing group.

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