2-nitroimidazole derivatives useful as radiosensitizers for hypo

Details 2-nitroimidazole derivatives useful as radiosensitizers for hypo 2-nitroimidazole derivatives useful as radiosensitizers for hypo

1987-07-31

1989-01-10

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

548336, 548339, 514300, 514326, 514183, 514215, 514397, 514398, 514302, 546113, 546210, 546115, 540476, 540480, 540521, 540524, C07D40112, C07D23391, A61K 31415, A61K 31445

Patent

active

047973978

ABSTRACT:
Certain .alpha.-[(2-nitro-1H-imidazol-1-yl)methyl]-aziridinylethanols and the corresponding aziridine-ring opened analogs are useful as radiation sensitizers for X-irradiation therapy of tumors.

REFERENCES:
patent: 4241060 (1980-12-01), Smithen
patent: 4282232 (1981-08-01), Agrawal
patent: 4581368 (1986-04-01), Ahmed et al.
patent: 4596817 (1986-06-01), Ahmed et al.
patent: 4631289 (1986-12-01), Ahmed et al.
G. E. Adams et al., Chemotherapy, vol. 7, pp. 187-206, Plenum Press, New York, 1976.

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