2-Nitroimidazole derivatives

Details 2-Nitroimidazole derivatives 2-Nitroimidazole derivatives

1972-07-26

1976-05-04

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240A, 2603068D, 2603092, 424270, 424273, C07D23391

Patent

active

039547892

ABSTRACT:
2-Nitroimidazole derivatives of the general formula ##SPC1##
Wherein R is a lower alkyl group and Y is a member of the group consisting of --CH.sub.2 OH, --CHO, CH.sub.3 CO--, vinyl, formylvinyl, styryl, substituted iminomethyl, 2-benzimidazolyl and 5-amino-1,3,4-thiadiazol-2-yl. The term "lower alkyl" designates aliphatic groups of from 1 to 4 carbon atoms; the term "substituted iminomethyl" designates nitrogen-containing functional derivatives of the aldehydic group. The compounds have antimicrobial activity.

REFERENCES:
patent: 3583985 (1971-06-01), Bambury et al.
patent: 3711495 (1973-01-01), Kulsa et al.
Cosar et al., Arzneimittel-Forschung, 1966, Vol. 16, pp. 23-29.
Chemical Abstracts Eighth Collective Index, Vols. 66-75, 1967-1971, Subjects Glucope -- Indena pp. 15577S, 15582S and 15590S, (1973).

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