2-NH-heteroarylimidazoles with antibacterial activity

Details 2-NH-heteroarylimidazoles with antibacterial activity 2-NH-heteroarylimidazoles with antibacterial activity

2005-09-13

2005-09-13

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S118000, C544S236000, C544S264000, C544S350000, C548S303700, C514S248000, C514S249000, C514S261100, C514S393000

Reexamination Certificate

active

06943175

ABSTRACT:
Compounds of formula (I):are inhibitors of bacterial methionyl tRNA synthetase and are of use in treating bacterial infections.

REFERENCES:
patent: 0 785 268 (1997-07-01), None
patent: WO 00/71522 (2000-11-01), None
Van der Wenden et al. (1995) European J. Pharma. 290:189-199.
Peyman et al. (2000) Angew. Chem. Int. Ed. 39(16):2874-2877.
Jarvest et al. (2002) J. Med. Chem. 45(10):1959-1962.
Iwao et al. (1992) Heterocycles 34(5):1031-1038.
Barlin et al. (1982) Aust. J. Chem. 35:2299-2306.
Fleischmann et al. (1995) Science 269:496-519.
Lespagnol et al. (1968) Ann. Pharm. Fr. 26(3):207-214 (and abstract in English).

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