2-Naphthyl acetic acid derivatives and compositions and methods

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2603457, 2603473, 260515P, 260516, 260558D, 260590C, 260592, 424248, 424250, 424267, 424274, 424283, 424285, 424304, 424308, 424312, 424317, 424324, C07C11900, C07C 8300

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039781160

ABSTRACT:
2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.

REFERENCES:
patent: 2279560 (1942-04-01), Dietrich
patent: 3479396 (1969-11-01), Buu-Hol et al.
patent: 3586713 (1971-06-01), Buu-Hol et al.

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