2-naphthamide derivatives and their therapeutic applications

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514319, 546184, 546192, 546195, 546205, 546206, 546248, A61K 31445, C07D21106, C07D21120

Patent

active

059858958

ABSTRACT:
The invention relates to 2-naphthamide derivatives, in the form of bases or of salts, corresponding to the following general formula (I): ##STR1## in which: the Z-Y entity represents an N--CH.sub.2, C.dbd.CH or CH--CH.sub.2 group;

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patent: 5254552 (1993-10-01), Abou-Gharbia et al.
patent: 5395835 (1995-03-01), Glase et al.
Nilsson et al. (J. Med. Chem. (1997), 40, 833-840) 1997.
Xavier Emonds-Alt et al. (Bioorganic & Medicinal Chemistry Letters, (1993) vol. 3, No. 5, pp. 925-930, 1993.
Glase et al. (Bioorganic & Medicinal Chemisty Letters, (1996), vol. 6, No. 12, pp. 1361-1366, 1996.

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