Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1978-12-20
1980-11-25
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
546202, A61K 31445, C07D41704, A61K 3138
Patent
active
042359163
ABSTRACT:
The present invention relates to the novel compound 2-methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene of the formula ##STR1## and its non-toxic acid addition salts, which compounds have strong and longlasting neuroleptic properties and, at the same time, a low degree of undesired side effects such as extrapyrimidal side effects.
The invention moreover relates to a method for the preparation of said novel compounds, pharmaceutical compositions containing same, which may be administered to animals, including human beings, orally or parentally.
Further the invention relates to a method for producing an antipsychotic effect in warmblooded animals by administering to said animals an antipsychotically effective amount of one of said novel compounds.
REFERENCES:
patent: 4086350 (1978-04-01), Zirkle
Janssen et al., "Arzneimittelforschung", vol. 17, pp. 841-854, (1967).
Creese et al., "Science", vol. 192, pp. 481-483, (1976).
Roos et al., "Life Sciences", vol. 3, pp. 351-360, (1964).
Bond Robert T.
Hueschen Gordon W.
Jiles Henry R.
Kefalas A/S
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