2-methyl-4-hexene-and 3-methyl-5-heptene-1,2-diol derivatives

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...

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435 79, 435192, 435964, 514 11, 530317, 530321, C12N 996, C12N 904, A61K 3700

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active

054016495

ABSTRACT:
2-methyl-4-hexene- and 3-methyl-5-heptene-l,2-diol derivatives are disclosed together with methods for preparing such derivatives. Where the derivative is a 2-methyl-4-nexene- or 3-methyl-5-heptene-l,2-diol conjugated to a label, the conjugates are useful in immunoassays. Where the 2-methyl-4-hexene or 3-methyl-5-heptene-l,2-diol is conjugated to an immunogenic carrier, the conjugates may be employed as an immunogen for use in the preparation of antibodies. The label conjugate and the antibodies can be utilized in an immunoassay for the determination or detection of cyclosporin in a sample suspected of containing cyclosporin.

REFERENCES:
patent: 3875011 (1975-04-01), Rubenstein
patent: 4096237 (1978-06-01), Li
patent: 4104367 (1978-08-01), Gomez et al.
patent: 4117118 (1978-09-01), Harri et al.
patent: 4123431 (1978-10-01), Soffer et al.
patent: 4206199 (1980-06-01), Fujino et al.
patent: 4384996 (1983-05-01), Bollinger
patent: 4396542 (1983-08-01), Wenger
patent: 4554351 (1985-11-01), Wenger
patent: 4608200 (1986-08-01), Khanna et al.
patent: 4608252 (1986-08-01), Khanna et al.
patent: 4639434 (1987-01-01), Wenger et al.
patent: 4686181 (1987-08-01), Dona
patent: 4727035 (1988-02-01), Mahoney
patent: 4764503 (1988-08-01), Wenger
patent: 5169773 (1992-12-01), Rosenthaler et al.
Fois Romano, Synthesis of a Fluorescent Derivative . . . J of Pharm Sci 80 (4) Apr. 1991, pp. 363-367.
Wolf, B. A.; et al.; Clin. Chem. 1989, 35(1), 120-124.
Vernillet, L.; et al.; Clin. Chem. 1989, 35(4), 608-611.
Ball, P. E.; et al.; Clin. Chem. 1988, 34(2), 257-260.
Schran, H. F.; et al.; Clin. Chem. 1987, 33(12), 2225-2229.
Sanghvi, A.; et al.; Clin. Chem. 1988, 34(9), 1904-1906.
McBride, J. H.; et al.; Clin. Chem. 1989, 35(8), 1726-1730.
Quesniaux, V.; et al.; Clin. Chem. 1987, 33(1), 32-37.
Christians, U.; et al.; Clin. Chem. 1988, 34(1), 34-39.
Donatsch, P.; et al.; J. Immunoassay 1981, 2(1), 19-32.
"Ciclosporin RIA-Kit, Instructions for Use"; Sandoz Ltd., Basle, Switzerland Jun. 1983.
Anonymous; Transplantation Proceedings 1990, 22(3), 1357-1361.
Quesniaux, V. F. J.; et al.; Mol. Immunology 1987, 24(11), 1159-1168.
Cacalano, N. A.; et al.; J. Immunological Methods, 1989, 118, 257-263.
Quesniaux, V.; et al.; Immunology Letters 1985, 9, 99-104.
Traber, R.; et al.; J. Antibiotics 1989, 42(4), 591-597.
Maurer, G.; et al.; Drug Metabolism and Disposition 1984, 12(1), 120-126.
Wisdom, G. B.; Clin. Chem. 1976, 22(8), 1243-1255.
Wenger, R. M.; Helv. Chim. Act. 1983, 66(7), 2308-2321.

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