2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives

Details 2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives 2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives

1987-09-04

1992-02-18

Ceperley, Mary E.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 792, 435 794, 435188, 435975, 436536, 436543, 436544, 436546, 436808, 436815, 436822, G01N 33533, G01N 33535, G01N 33543

Patent

active

050893904

ABSTRACT:
2-methyl-4-hexene- and 3-methyl-5-heptene-1,2-diol derivatives are disclosed together with methods for preparing such derivatives. Where the derivative is a 2-methyl-4-hexene- or 3-methyl-5-heptene-1,2-diol conjugated to a label, the conjugates are useful in immunoassays. Where the 2-methyl-4-hexene or 3-methyl-5-heptene-1,2-diol is conjugated to an immunogenic carrier, the conjugates may be employed as an immunogen for use in the preparation of antibodies. The label conjugate and the antibodies can be utilized in an immunoassay for the determination or detection of cyclosporin in a sample suspected of containing cyclosporin.

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Wisdom, G. B., "Enzyme-Immunoassay", Clinical Chemistry, vol. 22(8), pp. 1243-1255 (1976).

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