2-methyl-4-benzyl-5-oxazolidinone

Details 2-methyl-4-benzyl-5-oxazolidinone 2-methyl-4-benzyl-5-oxazolidinone

1987-07-31

1989-01-03

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D26308

Patent

active

047958162

ABSTRACT:
This invention relates to a new composition of matter known as 2-Methyl-4-benzyl-5-oxazolidinone and a method of preparation of the new composition comprising combining ethyl acetate and the azlactone of .alpha.-acetoaminocinnamic acid in the presence of a catalyst such as W-2 Raney nickel. By using the new composition of matter of this invention the synthesis of L-phenylalanine is shortened to fewer reactions and process steps from the current lengthy, multistep means of synthesis.

REFERENCES:
patent: 4137404 (1979-01-01), Batcho et al.
patent: 4414404 (1983-11-01), Roper
Seebach et al., CA 105-114946e.
Mar., Adv. Org. Chem. 2nd edition, pp. 860-861.
House, Modern Synthetic Reactions, pp. 236-239.

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