2-Methoxypropyl phosphate derivatives

Details 2-Methoxypropyl phosphate derivatives 2-Methoxypropyl phosphate derivatives

1984-03-02

1985-12-31

Sutto, Anton H.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260925, 260945, A23J 700

Patent

active

045620059

ABSTRACT:
Novel phospholipids, inclusive of pharmaceutically acceptable salts thereof, of the formula ##STR1## wherein R.sup.1 is an aliphatic hydrocarbon residue of 15 to 20 carbon atoms, R.sup.2 is an alkyl group of 1 to 4 carbon atoms and R.sup.3 is a hydrogen atom or an alkyl group of 1 to 4 carbon atoms, exhibit inhibitory activity to multiplication of tumor cells and are useful for inhibiting multiplication of tumor cells and prolonging the survival time of tumor-bearing warm-blooded animal.

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patent: 4426525 (1984-01-01), Hozumi et al.
patent: 4504474 (1985-03-01), Hanahan et al.
Takeda Yakuhin Kogy (1 page).
Toyama Chem KK (1 page).
Cancer Research, vol. 38, Effect of Lysolecithin and Analogs on Mouse Ascites Tumors, Tarnowski, Mountain, Stock, Munder, Weltzien and Westphal.
Cancer Research, vol. 39, Disturbance of Phospholipid Metabolism During the Selective Destruction of Tumor Cells Induced by Alkyl-Lysophospholipids, Modolell.

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