Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1978-10-04
1980-02-19
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
424267, 26032647, 542469, 546230, 546233, 546234, C07D20708, A61K 3140
Patent
active
041894952
ABSTRACT:
The invention provides novel 2-methoxy-benzamide derivatives of the formula: ##STR1## in which n is 1 or 2; R.sub.1 represents a cycloalkyl-alkyl radical of formula: ##STR2## a phenylalkyl radical of formula ##STR3## (in which m is an integer from 2 to 5, A is a linear or branched alkylene chain of 1 to 4 carbon atoms, and R.sub.4 is hydrogen, halogen, especially fluorine or chlorine, trifluoromethyl, or alkyl or alkoxy of 1 to 3 carbon atoms), CNCH.sub.2 --CH.sub.2 --, CH.tbd.C--CH.sub.2 --, ##STR4## R.sub.2 is either chlorine, SO.sub.2 R.sub.5 (in which R.sub.5 is alkyl of 1 to 4 carbon atoms), or SO.sub.2 NR.sub.6 R.sub.7 (in which, R.sub.6 and R.sub.7, which are identical or different, represent, independently of one another, hydrogen or alkyl of 1 to 4 carbon atoms); and R.sub.3 is hydrogen or alkyl of 1 to 4 carbon atoms; in the form of racemates or optical isomers, and their pharmaceutically acceptable acid addition salts, which are useful in the treatment of psychosomatic and pyschotic disturbances.
REFERENCES:
patent: 3342826 (1967-09-01), Miller et al.
patent: 3862139 (1975-01-01), Podesva et al.
patent: 3891671 (1975-06-01), Thominet
patent: 3975434 (1976-08-01), Bulteau et al.
patent: 4021567 (1977-05-01), Kaplan et al.
patent: 4029673 (1977-06-01), Bulteau et al.
Giudicelli Don P. R. L.
Jalfre Maurice
Kaplan Jean-Pierre
Manoury Philippe M. J.
Najer Henry
Lee Mary C.
Synthelabo
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