Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1975-12-16
1977-05-03
Gotts, Lewis
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
26032647, 26029375, 26029373, 26029377, 260240K, A01N 922
Patent
active
040215679
ABSTRACT:
The invention provides novel 2-methoxy-benzamide derivatives of the formula: ##STR1## in which n is 1 or 2; R.sub.1 represents a cycloalkyl-alkyl radical of formula:
(CH.sub.2).sub.m -CH-A- ,
a phenylalkyl radical of formula ##STR2## (in which m is an integer from 2 to 5, A is a linear or branched alkylene chain of 1 to 4 carbon atoms, and R.sub.4 is hydrogen, halogen, especially fluorine or chlorine, trifluoromethyl, or alkyl or alkoxy of 1 to 3 carbon atoms), CNCH.sub.2 -CH.sub.2 -, CH.tbd.C-CH.sub.2 -, ##STR3## R.sub.2 is either chlorine, SO.sub.2 R.sub.5 (in which R.sub.5 is alkyl of 1 to 4 carbon atoms), or SO.sub.2 NR.sub.6 R.sub.7 (in which, R.sub.6 and R.sub.7, which are identical or different, represent, independently of one another, hydrogen or alkyl of 1 to 4 carbon atoms); and R.sub.3 is hydrogen or alkyl of 1 to 4 carbon atoms; in the form of racemates or optical isomers, and their pharmaceutically acceptable acid addition salts, which are useful in the treatment of psychosomatic and psychotic disturbances.
REFERENCES:
patent: 3862139 (1975-01-01), Podesva et al.
Giudicelli Don Pierre Rene Lucien
Jalfre Maurice
Kaplan Jean-Pierre
Manoury Philippe Michel Jacques
Najer Henry
Gotts Lewis
Owens Cary
Synthelabo
Wegner Harold C.
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