2-mercapto-imidazole derivatives substituted in position 4 (or 5

Details 2-mercapto-imidazole derivatives substituted in position 4 (or 5 2-mercapto-imidazole derivatives substituted in position 4 (or 5

1997-09-15

2000-05-02

McKane, Joseph K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424 59, 426545, 252402, 252405, 514252, 514392, 544370, 5483114, 5483164, 5483241, 5483245, 5483251, A61K 742, A61K 31415, C07D23384, C07D40312

Patent

active

060569654

ABSTRACT:
The invention relates to 2-mercaptoimidazole derivatives substituted in the 4(or 5)-position.
These 2-mercaptoimidazole derivatives are of the general formula (I) below: ##STR1## wherein: R.sub.1, R.sub.2, R.sub.5, R.sub.7 and R.sub.8 are hydrogen, a lower alkyl, an aralkyl or a substituted aralkyl, wherein at least one of R.sub.1 and R.sub.2 is hydrogen;

REFERENCES:
patent: 4898878 (1990-02-01), Shapiro et al.
CA 96:57746j Heme concentrate. Lindroos, p. 368, 1982.
CA 112:2268248 Photosensitive . . . production. Aoshima et al., p. 679, 1990.
CA 117: 107204f Assessment of . . . inhibitors. Lueoend et al., p. 421, 1992.
Archives of Biochemistry and Biophysics, vol. 288, No. 1, Jul. 1991, "The Antioxidant Action of Ergothioneine".
Biochemical Pharmacology, vol. 36, No. 9, May 1, 1987, "Antioxidant Properties of 2-Imdazolones and 2-Imidazolthiones".
R.A.F. Bullerwell, et al., "2-Mercaptoglyoxalines. Part VIII.* The Preparation of 2-Mercaptoglyoxalines from Glutamic Acid", 1953.
Archives of Biochemistry and Biophysics, vol. 281, No. 1, Aug. 15, 1990, "The Reduction of Ferryl Myoglobin by Ergothioneine: A Novel Function for Ergothioneine".

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