Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1976-08-20
1977-11-01
Hines, Robert V.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
260268C, 26029373, 26032642, 2603265S, 260501, 260 19, 260515M, 260544N, 260558S, 260559D, 260559T, 2605709, 424250, 424267, 424274, 424316, 560 9, A01N 920, A01N 924
Patent
active
040566323
ABSTRACT:
Compounds, pharmaceutical preparations containing same, and method of treating depression in mammals, the compounds being of the formula I ##STR1## or an acid addition salt thereof, particularly a pharmacologically or pharmaceutically acceptable salt thereof, where R and R.sup.1 are the same or different and are each hydrogen or lower alkyl, or R and R.sup.1 taken together are (CH.sub.2).sub.X where X is 4 or 5, or NRR.sup.1 is ##STR2## where Y is 3 or 4 and R.sup.3 is hydrogen or lower alkyl, or NRR.sup.1 is ##STR3## where R.sup.2 is hydrogen or lower alkyl, in the above lower alkyl has 1 to 4 carbons and may be straight or branched and n and m are the same or different and are 1, 2, or 3.
REFERENCES:
patent: 2454260 (1968-11-01), Steiger
patent: 3514480 (1970-05-01), Fields
patent: 3803143 (1974-04-01), Tanaka et al.
patent: 3824243 (1974-07-01), Henderson
patent: 3927039 (1975-12-01), Yale
patent: 3997540 (1976-12-01), Mehta et al.
Brieaddy et al., "Abstracts A.C.S.", 6th Northeast Regional Meeting, p. 65, Aug. 18-21, 1974.
Brieaddy Lawrence Edward
Mehta Nariman Bomanshaw
Brown Donald
Burroughs Wellcome Co.
Hines Robert V.
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