2-Hydroxyaclacinomycin A and 2-hydroxyaklavinone and process for

Details 2-Hydroxyaclacinomycin A and 2-hydroxyaklavinone and process for 2-Hydroxyaclacinomycin A and 2-hydroxyaklavinone and process for

1980-09-05

1983-05-31

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 424181, 435 78, 260365, C07H 1524, A61K 3171, C12P 1956

Patent

active

043861989

ABSTRACT:
New anthracycline compounds, 2-hydroxyaclacinomycin A having potent antitumor activity and lower toxicity, 2-hydroxyaklavinone as an useful precursor for producing anthracycline glycosides, and a process for the production thereof by microbial conversion method are disclosed.

REFERENCES:
patent: 3988315 (1976-10-01), Umezawa et al.
patent: 4020270 (1977-04-01), Arcamone et al.
patent: 4144329 (1979-03-01), Umezawa et al.

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