2-Hydroxy-mutilin carbamate derivatives for antibacterial use

Details 2-Hydroxy-mutilin carbamate derivatives for antibacterial use 2-Hydroxy-mutilin carbamate derivatives for antibacterial use

2005-12-06

2005-12-06

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S357000, C546S285000, C546S206000, C560S256000, C544S281000, C544S294000, C544S410000, C544S350000, C544S224000, C548S194000

Reexamination Certificate

active

06972297

ABSTRACT:
2-(S)-hydroxymutilin carbamate derivatives of formula (I), in which R1is a 5- or 6-membered optionally substituted heteroaryl group; and R2is vinyl or ethyl, are useful in the treatment of bacterial infections

REFERENCES:
patent: 774419 (2002-02-01), None
patent: 2 771 008 (1999-05-01), None
patent: WO 97/25309 (1997-07-01), None
patent: WO 98/05659 (1998-02-01), None
patent: WO 99/21855 (1999-05-01), None
patent: WO 00/07974 (2000-02-01), None
Berner, et al., “Chemie der Pleuromutiline, 3. Mitt. Synthese des 14-0-Acetyl-19,20-dihydro-A-nor-mutilins”, (1981), Monatshefte fur Chemie, 112, pp. 1441-1450.
Schulz et al., “Chemie der Pleuromutiline-VI...”, (1984), Tetrahedron, 40(5), pp. 905-917.

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