2-Hydroxy-3-nitro-1,4-naphthoquinones for the prophylaxis of cer

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 3112

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active

040176398

ABSTRACT:
Substituted naphthoquinones of the formula (I) and pharmaceutically acceptable salts thereof wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent alkyl, aryl, alkoxy, hydroxy, hydrogen or halogen or any two of the groups R.sub.1, R.sub.2, R.sub.3 and R.sub.4 taken together complete a carbocyclic ring, have useful anti-allergy activity in mammals.

REFERENCES:
patent: 3833726 (1974-09-01), Schwender et al.
patent: 3920845 (1975-11-01), Smith et al.
Vladimirtsev et al., Chemical Abstracts 73:1190f, (1970).
Ikeda et al., Chemical Abstracts 50:3358d, (1956).

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