2-Heterocyclic alkylamino-3-nitropyrroles

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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546281, 546208, 546256, 546261, 546264, 446278, 548336, 548134, 548136, 548205, 548214, 548235, 548247, 548269, 2603265SM, 2603265D, 2603269, 424273R, 424269, 424270, 424272, 424274, A61K 31415, A61K 3144, C07D40112, C07D40312

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042384940

ABSTRACT:
3-Nitro-2-substituted aminopyrroles are histamine H.sub.2 -receptor antagonists. The 2-position substituent is a fully-unsaturated heterocyclyl alkyl group preferably with with alkyl group interrupted by sulfur or oxygen. The 4- and 5-positions of the pyrrole ring can also be substituted.

REFERENCES:
patent: 3518251 (1970-06-01), Gatzi
patent: 3932644 (1976-01-01), Durant et al.
patent: 3953460 (1976-04-01), Durant et al.
patent: 4128658 (1978-12-01), Price et al.
patent: 4154834 (1979-05-01), Brown et al.

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