Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-07-08
1976-04-06
Gallagher, Richard J.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260465E, 260999, C07D23926, C07D23934
Patent
active
039489159
ABSTRACT:
A process for preparing a 2-halopyrimidine derivative represented by the formula: ##SPC1##
Wherein R.sup.2 represents a hydrogen atom, a halogen atom, a lower alkyl group, an aryl group, and an amino group and R.sup.4 represents a lower alkyl group and X represents a halogen atom, which comprises reacting cyanoacetimidate derivative represented by the formula: ##EQU1## wherein R.sup.2 and R.sup.4 represent the same as above and M represents a mineral acid residue with cyanamide, to produce an N-cyanocyanoacetimidate ##EQU2## represented by the formula: WHEREIN R.sup.2 and R.sup.4 represent the same as above, and thereafter reacting said N-cyanocyanoacetimidate with a hydrogen halide.
REFERENCES:
Nitta et al., "Chemical Abstracts," Vol. 63, 1965, Col. 11556g.
Grigat et al., "Chemical Abstracts," Vol. 64, 1966, Col. 2086g.
Hirayama Tadamasa
Kamada Masahiro
Tsurumi Hideaki
Daiichi Seiyaku Co., Ltd.
Gallagher Richard J.
Turnipseed James H.
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