2-Halopyrimidine derivatives and a method for their preparation

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260465E, 260999, C07D23926, C07D23934

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active

039489159

ABSTRACT:
A process for preparing a 2-halopyrimidine derivative represented by the formula: ##SPC1##
Wherein R.sup.2 represents a hydrogen atom, a halogen atom, a lower alkyl group, an aryl group, and an amino group and R.sup.4 represents a lower alkyl group and X represents a halogen atom, which comprises reacting cyanoacetimidate derivative represented by the formula: ##EQU1## wherein R.sup.2 and R.sup.4 represent the same as above and M represents a mineral acid residue with cyanamide, to produce an N-cyanocyanoacetimidate ##EQU2## represented by the formula: WHEREIN R.sup.2 and R.sup.4 represent the same as above, and thereafter reacting said N-cyanocyanoacetimidate with a hydrogen halide.

REFERENCES:
Nitta et al., "Chemical Abstracts," Vol. 63, 1965, Col. 11556g.
Grigat et al., "Chemical Abstracts," Vol. 64, 1966, Col. 2086g.

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