2-Halopropionic acid and its derivatives

Details 2-Halopropionic acid and its derivatives 2-Halopropionic acid and its derivatives

1976-09-30

1978-02-14

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260465F, 26050117, 260516, 260520C, 260559D, 260562P, 260571, 260612R, 260599, 560 9, C07C 6976

Patent

active

040740579

ABSTRACT:
Compounds of the formula: ##STR1## wherein R.sup.1 represents hydrogen, lower alkyl having 1 to 5 carbon atoms, halogen, hydroxyl, lower alkoxy having 1 to 4 carbon atoms or trifluoromethyl; R.sup.2 and R.sup.3 are the same or different and each represents hydrogen or a lower alkyl having 1 to 5 carbon atoms; Y represents an alkylenethio group having 1 to 6 carbon atoms, alkyleneoxy having 1 to 6 carbon atoms, or alkylenedioxy having 1 to 6 carbon atoms; Z represents a carboxyl group or a group convertible to carboxyl and n is 1 or 2. The compounds have utility in treatment of hyperlipemia and diabetes.

REFERENCES:
patent: 2128975 (1938-09-01), Van Duzee et al.
patent: 3649679 (1972-03-01), Marshall
patent: 3983164 (1976-09-01), Thorne

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