2-halomethyl derivatives of 2-amino acids

Details 2-halomethyl derivatives of 2-amino acids 2-halomethyl derivatives of 2-amino acids

1982-06-25

1988-05-10

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540528, 560168, 560169, 560 39, 560 41, 562448, 562450, 562560, 562561, C07C10124, C07D21176

Patent

active

047436913

ABSTRACT:
2-(Fluoromethyl or chloromethyl)-2,5-diaminopentanoic acid, 2-(fluoromethyl or chloromethyl)-2,6-diaminohexanoic acid, and 2-fluoromethyl-2-amino-5-guanidinopentanoic acid, and certain derivatives thereof, are inhibitors of ornithine decarboxylase. Methods of preparing the compounds and derivatives are also described.

REFERENCES:
patent: 2662915 (1953-12-01), Lontz et al.
patent: 3168558 (1965-02-01), Kurhajec et al.

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