Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1981-01-14
1986-09-30
Milestone, Norma S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546315, C07D21361
Patent
active
046148337
ABSTRACT:
2-Halo-pyridines of the general formula I ##STR1## wherein X is Cl or Br; A is .dbd.0 or ##STR2## Ar is phenyl or substituted phenyl of the general formula ##STR3## in which n is 0, 1, 2 or 3; R is alkyl C.sub.1-4, alkoxy C.sub.1-4, phenoxy, alkylthio C.sub.1-4, halogen especially F and Cl, OH or C.sub.6 H.sub.5 ; and their salts, addition compounds and precursors (prodrugs).
Furthermore the invention is directed to the production of these compounds and pharmaceuticals containing them.
REFERENCES:
patent: 3467662 (1969-09-01), Frey et al.
patent: 3931205 (1976-01-01), Nakanishi et al.
patent: 3956344 (1976-05-01), Von Bebenburg et al.
patent: 4304941 (1981-12-01), Lee et al.
PTO-Translation of Japanese Kokai Patent Publication No. 51-95097, published Aug. 20, 1976.
K. Beelitz et al, Liebigs Ann. Chem. (1979) pp. 1081-1083.
Chemical Abstracts, vol. 92 (1980) 6440q.
Chemical Abstracts, vol. 86 (1977) 171,424w.
Codina Puigmarti Jose M.
Matas Ricardo D.
Repolles Jose M.
Sera Jorge S.
Lacer S.A.
Milestone Norma S.
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