2-Halo-2'-deoxyadenosines as therapeutic agents against malignan

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

536 2763, 536 277, A61K 3170

Patent

active

054242967

ABSTRACT:
A process for the treatment of malignant astrocytoma in mammals is disclosed that utilizes a 2-halo-2'-deoxyadenosine derivative as the active treating agent.

REFERENCES:
patent: 4719295 (1988-01-01), Cook et al.
patent: 4826823 (1989-05-01), Cook et al.
patent: 5106837 (1992-04-01), Carson et al.
patent: 5310732 (1994-05-01), Carson et al.
Hine, Physical Organic Chemistry, 2nd ed., McGraw-Hill Book Co., Inc., New York (1962) p. 87.
Avery et al., "Biochemical Pharmacology of 2-Chlorodeoxyadenosine in Malignant Human Hematopoietic Cell Lines and Therapeutic Effects of 2-Bromodeoxyadenosine in Combinations in Mice," Cancer Research, 49, 4972-4978 (1989).
Cory et al., "Leukemia L1210 Cell Lines Resistant to Ribonucleotide Reductase Inhibitors," Cancer Research, 48(4), 839-843 (1988).
T. Beardsley, "Trends in Cancer Epidemiology--A War Not Won," Scientific American, 270(1), 130-138 (1994).
Saven et al., "2-Chlorodeoxyadenoisine Dose Escalation in Nonhematologic Malignancies," J. Clinical Oncology, 11(4), 671-678 (1993).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

2-Halo-2'-deoxyadenosines as therapeutic agents against malignan does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-Halo-2'-deoxyadenosines as therapeutic agents against malignan, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-Halo-2'-deoxyadenosines as therapeutic agents against malignan will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1309398

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.