Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1993-04-15
1995-06-13
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 2763, 536 277, A61K 3170
Patent
active
054242967
ABSTRACT:
A process for the treatment of malignant astrocytoma in mammals is disclosed that utilizes a 2-halo-2'-deoxyadenosine derivative as the active treating agent.
REFERENCES:
patent: 4719295 (1988-01-01), Cook et al.
patent: 4826823 (1989-05-01), Cook et al.
patent: 5106837 (1992-04-01), Carson et al.
patent: 5310732 (1994-05-01), Carson et al.
Hine, Physical Organic Chemistry, 2nd ed., McGraw-Hill Book Co., Inc., New York (1962) p. 87.
Avery et al., "Biochemical Pharmacology of 2-Chlorodeoxyadenosine in Malignant Human Hematopoietic Cell Lines and Therapeutic Effects of 2-Bromodeoxyadenosine in Combinations in Mice," Cancer Research, 49, 4972-4978 (1989).
Cory et al., "Leukemia L1210 Cell Lines Resistant to Ribonucleotide Reductase Inhibitors," Cancer Research, 48(4), 839-843 (1988).
T. Beardsley, "Trends in Cancer Epidemiology--A War Not Won," Scientific American, 270(1), 130-138 (1994).
Saven et al., "2-Chlorodeoxyadenoisine Dose Escalation in Nonhematologic Malignancies," J. Clinical Oncology, 11(4), 671-678 (1993).
Piro Lawrence D.
Saven Alan
Crane L. Eric
Robinson Douglas W.
The Scripps Research Institute
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