2-guanidino-4-(2-methyl-4-imidazolyl)thiazoles in the treatment

Details 2-guanidino-4-(2-methyl-4-imidazolyl)thiazoles in the treatment 2-guanidino-4-(2-methyl-4-imidazolyl)thiazoles in the treatment

1985-08-09

1986-05-27

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31425

Patent

active

045915954

ABSTRACT:
2-Guanidino-4-(2-methyl-4-imidazolyl)thiazole and 2-(N-pentyl-N'-guanidino)-4-(2-methyl-4-imidazolyl)thiazole, histamine-H.sub.2 antagonist useful as a gastric acid antisecretory and antiulcer agents, are also useful per se in the treatment of rheumatoid arthritis.

REFERENCES:
patent: 4374843 (1983-02-01), LaMattina et al.

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