2-guanidino-4-(2-furyl) thiazoles as antiulcer agents

Details 2-guanidino-4-(2-furyl) thiazoles as antiulcer agents 2-guanidino-4-(2-furyl) thiazoles as antiulcer agents

1988-04-19

1989-03-21

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548193, C07D41704, A61K 31425

Patent

active

048143413

ABSTRACT:
A series of novel thiazole compounds, having a guanidino or substituted guanidino group at the 2-position and a 5-(N,N-disubstituted aminomethyl)-2-furyl group at the 4-position. The compounds of the invention are useful for administration to mammals for prophylactic or curative treatment of peptic ulcers.

REFERENCES:
patent: 3950333 (1976-04-01), Durant et al.
patent: 4128658 (1978-12-01), Price et al.
patent: 4315009 (1982-02-01), Jones et al.
patent: 4374843 (1983-02-01), LaMattina et al.
patent: 4435396 (1984-03-01), LaMattina et al.

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