2-Fluoromethyl-3-o-tolyl-6-amino-4(3H)-quinazolinone

Details 2-Fluoromethyl-3-o-tolyl-6-amino-4(3H)-quinazolinone 2-Fluoromethyl-3-o-tolyl-6-amino-4(3H)-quinazolinone

1974-09-30

1976-06-29

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260251QA, 2602565R, 260558R, 260558A, 424250, C07D23991

Patent

active

039667316

ABSTRACT:
N-(2-amino-5-nitrobenzoyl)-o-toluidine is condensed with fluoroacetic acid or a functional derivative thereof. N-(2-fluoroacetamido-5-nitrobenzoyl)-o-toluidine obtained by said condensation reaction is dehydrated to produce 2-fluoromethyl-3-(o-tolyl)-6-nitro-4(3H)-quniazolinone, which is then subjected to reduction reaction. 2-fluoromethyl-3-(o-tolyl)-6-amino-4(3H)-quinazolinone thus obtained and a pharmaceutically acceptable acid addition salt thereof are useful as central muscle relaxants, minor tranquilizers, anti-convulsants, analgesics and/or anti-inflammatory agents.

REFERENCES:
patent: 3414573 (1968-12-01), Breuer
Boehringer Co., "Chemical Abstracts" of Fr. 1,412,615, 1965, p. 5112ff, vol. 64.
Burger, "Medicinal Chemistry," p. 43, 1963.

Affiliated with

Also associated with

Rating

2-Fluoromethyl-3-o-tolyl-6-amino-4(3H)-quinazolinone does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-Fluoromethyl-3-o-tolyl-6-amino-4(3H)-quinazolinone, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-Fluoromethyl-3-o-tolyl-6-amino-4(3H)-quinazolinone will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1277222