2-Diphenylmethyleneamino-3-indolylpropionitrile and alkyl esters

Details 2-Diphenylmethyleneamino-3-indolylpropionitrile and alkyl esters 2-Diphenylmethyleneamino-3-indolylpropionitrile and alkyl esters

1981-03-26

1983-08-16

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548496, 548505, C07D20918, C07D20920

Patent

active

043992897

ABSTRACT:
Novel indole derivatives of the general formula I can be obtained by reacting, directly or indirectly, N,N-dimethyl-3-indolemethylamine with a Schiff base of the general formula II, ##STR1## in which R.sup.1 is cyano or methoxycarbonyl, ethoxycarbonyl, propoxycarbonyl or butoxycarbonyl, and .phi. is phenyl. The successive hydrolysis of the indole derivatives of the general formula I in the presence of an acid and of a base gives tryptophane.

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