Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1980-05-02
1981-07-28
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424266, 546224, 546291, 546309, A61K 31445, C07D21160
Patent
active
042810060
ABSTRACT:
Compounds having the formula ##STR1## wherein A is a bond or C.sub.1-4 alkylene; R.sup.1, R.sup.2 and R.sup.3 are independently a halogen atom, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 alkylthio, CF.sub.3, SCF.sub.3 or OCF.sub.3 ; R.sup.4 is a hydrogen atom or C.sub.1-4 alkyl; and n, m and q are independently an integer from 0 to 3; and pharmaceutically acceptable acid addition salts thereof, are useful for the treatment of gastrointestinal hypersecretion.
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Grisar, J., et al., J. Med. Chem., 1973, 16(8), 885-893.
Benson, R., et al., J. Am. Chem. Soc., 70, 2115-2118 (1948).
Aldrich Chemical Co., Catalog 20 (1980), pp. 163, 165, 237, 208, 132, 133, 303, 304, 312, 313, 314, 315, 319, 327, 334, 335, 344, 345, 351, 352, 364, 365, 376, 377, 378, 908, 909, 911, 921, 926, 927, 928, 930 and 931.
Grisar J. Martin
Wiech Norbert L.
Richardson-Merrell Inc.
Schwartz Richard A.
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