Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-01-20
1976-05-11
Brown, Johnnie R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
195 80R, 424181, C07H 1522
Patent
active
039562751
ABSTRACT:
A method of making new derivatives of streptomycin by mutational biosynthesis. A mutant of Streptomyces griseus makes streptomycin production dependent on streptidine addition.
A new antibiotic, deoxystreptomycin, is disclosed.
REFERENCES:
patent: 2837510 (1958-06-01), Yabuta et al.
patent: 3743634 (1973-07-01), Woo
Bock "The Jour. of Antibiotics," Vol. XXVII, No. 2, 1974, pp. 139-140.
Demain Arnold L.
Nagaoka Kozo
Brown Johnnie R.
Lorusso Anthony M.
Massachusetts Institute of Technology
Santa Martin M.
Smith, Jr. Arthur A.
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