2'-deoxy-5-ethynyluridine-3',5'-diestens for treatment of VZV an

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

536 23, A61K 31505, C07H 1906

Patent

active

048639060

ABSTRACT:
The present invention relates to the use of 2'-deoxy-5-ethynyluridine and its pharmaceutically acceptable derivatives in the treatment and prophylaxis of varicella zoster virus and cytomegalovirus infections. Also provided are pharmaceutical formulations and processes for the preparation of the compounds according to the invention.

REFERENCES:
patent: 4247544 (1981-01-01), Bergstrom et al.
patent: 4424211 (1984-01-01), Jones et al.
patent: 4544740 (1985-10-01), Szaboles nee Borbas et al.
patent: 4594339 (1986-06-01), Lopez et al.
Journal of the Chemical Society, Perkin Transaction I, 1978, pp. 1263-1267.
Journal of the Chemical Society, Perkin Transaction I, 1981, pp. 1665-1670.
Tetrahedron, vol. 36, 1980, pp. 155-158.
Chemical Abstracts, vol. 91, 1979, pp. 26 and 27, abstract No. 133836c and Proc. Natl. Acad. Sci., U.S.A., 1979, 76(6), 2947-51.
Journal of Organic Chemistry, vol. 48, No. 11, 1983, pp. 1854-1862, Am. Chem. Soc. US.
DeClercq, Methods and Findings in Experimental Clinical Pharmacology, vol. 2(5), pp. 253-267, 1980.
Barr et al., J. Chem. Soc., Perkin I, pp. 1263-1267, 1978.
Perman et al., Tett. Lett., pp. 2427-2430, 1976.
Robins et al., J. Org. Chem., vol. 48, pp. 1854-1862, 1983.
Robins et al., Can. J. of Chem., vol. 60, pp. 554-557, 1982.
Millen et al., J. of Virology, vol. 23, pp. 679-684, 1977.
Streissle et al., Advances in Virus Research, vol. 30, pp. 83-138, 1985, Academic Press.
Walker et al., Nucleic Acids Research Symposium Series, No. 16, pp. 291-294, 1985.
De Clercq et al., J. of Infections Diseases, vol. 141, pp. 563-574, 1980.
De Clercq et al., Proc. Nat. Acad. Sci., U.S.A., vol. 76, pp. 2947-2951, 1979.
DeClercq et al., Molecular Pharmacology, vol. 21, pp. 217-223, 1982.
Saran et al., Quantum Chemistry, Symposium, No. 9, pp. 247-257, 1982.
Perlman et al., J. Med. Chem., vol. 28, pp. 741-748, 1985.
De Clercq et al., Pharmaceutical Therspies, vol. 26, pp. 1-44, 1984.
Shealy et al., J. Med. Chem., 29, 79-84, 1986.
DeClercq et al., Molecular Pharmacology, vol. 19, pp. 321-330, 1981.
DeClercq et al., J. Med. Chem., vol. 26, pp. 661-666, 1983.
Perman et al., Tett. Lett., 1976, pp. 2427-2430.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

2'-deoxy-5-ethynyluridine-3',5'-diestens for treatment of VZV an does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2'-deoxy-5-ethynyluridine-3',5'-diestens for treatment of VZV an, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2'-deoxy-5-ethynyluridine-3',5'-diestens for treatment of VZV an will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-243543

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.