2-deoxy-3-phosphonylmethyl nucleosides

Details 2-deoxy-3-phosphonylmethyl nucleosides 2-deoxy-3-phosphonylmethyl nucleosides

1984-03-02

1987-08-25

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 28, 536 29, C07H 1512

Patent

active

046894071

ABSTRACT:
The invention relates to 2'-deoxy-3'-phosphonylmethyl nucleosides that are not substituted in the 2'-position.

REFERENCES:
patent: 3446793 (1969-05-01), Jones et al.
Harper's Review of Biochemistry, 18th Edition, 1981, p. 364.
Jones et al., Synthesis of Isosteric Phosphonate Analogs of Some Biologically Important Phosphodiesters, J Am Chem Soc 92, 5510 (1970a).
Jones et al., 3'-Deoxy-3'-(Dihydroxyphosphinylmethyl) nucleosides . . . , J Am Chem Soc 92, 5511 (1970b).

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