2-deoxy-2',2'-difluoro-inosine and 5'O-derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 46, C07H 19173, A61K 3170

Patent

active

050617931

ABSTRACT:
2'-deoxy-2',2'-difluoro-inosine and 5'-O alkyl derivatives are disclosed as inhibitors of neoplasms.

REFERENCES:
patent: 3705147 (1972-12-01), Robins et al.
patent: 3870700 (1975-03-01), Kotick et al.
patent: 4145531 (1979-03-01), Eckstein et al.
patent: 4211773 (1980-07-01), Lopez et al.
patent: 4526988 (1985-07-01), Hertel
patent: 4692434 (1987-09-01), Hertel
patent: 4808614 (1989-02-01), Hertel
Remington's Pharmaceutical Sciences, 16th ed., Osol ed., Mack Publishing Company, 424 (1980).
Sweeney et al., Cancer Research 38, 2886-2891 (1978).
Miller et al., Journal of Medicinal Chemistry, vol. 20, No. 3, 409-413 (1977).
Frei, Cancer research 45, 6523-6537 (1985).
Adamson et al., Chem. Abst., 75, 1971, 98773a.
Brox et al., Chem. Abst., 82, 1975, p25625p.
Chou et al., Cancer Res., 42, 3957-63 (1982).
Burchenal et al., Cancer Res., 42, 2598-600 (1982).
Martin et al. (1987) J. Pharm. Sci., vol. 76, No. 2, pp. 180-184.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

2-deoxy-2',2'-difluoro-inosine and 5'O-derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-deoxy-2',2'-difluoro-inosine and 5'O-derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-deoxy-2',2'-difluoro-inosine and 5'O-derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1401463

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.