2-Decarboxy-2-tetrazolyl-4-halo-5,9-epoxy-9-deoxy-PGF.sub.1 comp

Details 2-Decarboxy-2-tetrazolyl-4-halo-5,9-epoxy-9-deoxy-PGF.sub.1 comp 2-Decarboxy-2-tetrazolyl-4-halo-5,9-epoxy-9-deoxy-PGF.sub.1 comp

1979-09-07

1981-09-15

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

542426, 542431, 424269, C07D40502

Patent

active

042898889

ABSTRACT:
The present invention relates to novel 2-decarboxy-2-tetrazolyl-4-halo-5,9-epoxy-9-deoxy-PGF.sub.1 compounds, which are intermediates useful for the preparation of corresponding 5,9.alpha.-epoxy-9-deoxy-PGF.sub.1 and 5,9-epoxy-9-deoxy-4,5-didehydro-PGF.sub.1 compounds. These end products are employed for induction of a variety of prostacyclinlike pharmacological effects. Accordingly, these end products are useful pharmacological agents for the same purposes for which prostacyclin is employed.

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