2-Decarboxy-2-hydroxymethyl-deoxy-9,10-didehydro-PGD.sub.2 analo

Details 2-Decarboxy-2-hydroxymethyl-deoxy-9,10-didehydro-PGD.sub.2 analo 2-Decarboxy-2-hydroxymethyl-deoxy-9,10-didehydro-PGD.sub.2 analo

1977-04-06

1980-05-20

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568380, C07C 4956

Patent

active

042039240

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

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