2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-PGF.sub.1.alph

Details 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-PGF.sub.1.alph 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-PGF.sub.1.alph

1977-03-17

1978-06-27

Schwartz, Gerald A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

C07C 3500

Patent

active

040975371

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
derwent Farmdoc CPI No. 22,600 (29-3-65)

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