Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Patent
1980-03-03
1981-08-11
Mars, Howard T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
568374, C07C 49633, C07C 3531
Patent
active
042835755
ABSTRACT:
The present invention provides novel 2-decarboxy-2-hydroxymethyl-19-hydroxy-6a-carba-PGI.sub.1 compounds which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
REFERENCES:
Johnson et al., Prostaglandins, vol. 12, pp. 915-928, (1976).
Johnson et al., J.A.C.S., vol. 100, pp. 7690-7704, (1978).
Fried et al., Proc. Nat'l. Acad. Sci., U.S.A., vol. 74, pp. 2199-2203.
Nicolaou et al., J.C.S. Chem. Comm., 1977, pp. 331-332, (1977).
Nelson et al., J.A.C.S., vol. 99, pp. 7362-7363, (1977).
Kojima et al., Tetra Letters, p. 1978, (1977).
Kojima et al., Tetra Letters, pp. 3743-3746, (1978).
Johnson, Prostaglandins, vol. 15, pp. 737-740, (1978).
Armitage Robert A.
Mars Howard T.
Reamer James H.
The Upjohn Company
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