2-Decarboxy-2-hydroxymethyl-19-hydroxy-6-oxo-PGF.sub.1 compounds

Details 2-Decarboxy-2-hydroxymethyl-19-hydroxy-6-oxo-PGF.sub.1 compounds 2-Decarboxy-2-hydroxymethyl-19-hydroxy-6-oxo-PGF.sub.1 compounds

1980-03-03

1981-07-28

Mars, Howard T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568379, C07C 49534, C07C 49297

Patent

active

042812054

ABSTRACT:
The present invention provides novel 2-decarboxy-2-hydroxymethyl-19-hydroxy-6-oxo-PGF.sub.1 compounds which are useful for pharmacological purposes, e.g., anti-asthmatic indications.

REFERENCES:
Johnson et al, Prostaglandins, vol. 12, pp. 915-928 (1976).
Johnson et al, J.A.C.S., vol. 100, pp. 7690-7704 (1978).
Fried et al, Proc. Nat'l. Acad. Sci. U.S.A., vol. 74, pp. 2199-2203.
Nicolaou et al, J.C.S. Chem. Comm., 1977, pp. 331-332 (1977).
Nelson et al, J.A.C.S., vol. 99, pp. 7362-7363 (1977).
Kojima et al, Tetra Letters, p. 1978 (1977).
Kojima et al, Tetra Letters, pp. 3743-3746 (1978).
Johnson, Prostaglandins, vol. 15, pp. 737-740 (1978).

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